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Augustine Therapeutics: bridging the valley of death with VIB Discovery Sciences

Augustine Therapeutics is one of VIB’s latest spinoffs, developing a first-in-class drug for Charcot-Marie-Tooth disease. The company recently announced a seed-funding round of €4.2 million, led by V-Bio Ventures. We spoke to several of the key persons in Augustine about how the startup is tackling the “Valley of Death”: the no-man’s-land between academia and industry where many potential therapies often fail.
Animals have been used throughout history to understand human physiology and to resolve scientific questions related to health and disease. Nowadays, however, both scientists and the public are pushing for better options to animal testing, and so increasing efforts are being put into developing and promoting these alternative methods. Two such initiatives are being spearheaded by the Vrije Universiteit Brussel (VUB): The Innovation Centre for 3R Alternatives (IC-3Rs) and the RE-Place project.
Leuven, Belgium, Feb 20th 2020 - Montis Biosciences announces its launch with €8,4 million in seed financing from an international investor syndicate to investigate interactions between perivascular macrophages and tumor vasculature. The company’s mission is to exploit these cellular interactions with therapeutics to drive and sustain immune reactions against solid tumors.
Inari Agriculture has been awarded the 2020 Newcomer of the Year Trophy by Flanders Investment & Trade (FIT). Inari (US) opened its first foreign R&D branch in Ghent’s biotech valley just over a year ago. Since then, the Belgian team has been hard at work developing plants that can address both growing global food requirements and climate change. They’re approaching the challenge with both the latest genetic techniques and with a fresh perspective on how a business should be run.
Ghent, Belgium, February 10, 2020 - PharmaFluidics NV, an innovative player in the field of analytical chromatography, announces a product range extension into capillary flow rate liquid chromatography (capillary LC).  PharmaFluidics initiates commercial supplies of its new µPAC™ capLC column, bringing unprecedented sensitivity, reproducibility and robustness to a new range of customers worldwide, including the biopharmaceutical industry. PharmaFluidics’ unique high-resolution µPAC™ micro-Chip technology enables separation and detection of individual compounds in complex biological samples such as biopsies, proteome digests, culture media or biopharmaceutical actives, with unmatched precision.
The biotech Bioxodes is using a molecule derived from tick saliva to stop blood clots. The Walloon company is focused on preventing thrombosis during procedures involving medical devices. The current gold-standard anticoagulant can cause unwanted bleeding and side effects; could a molecule derived from ticks really be safer?
With the Belgian biotech landscape blooming, BioVox reached out to some of the investors in our network to see what their predictions are for the coming year. From trends to companies to keep an eye on, here’s their take on 2020!
Researchers have developed a new antibacterial strategy that weakens bacteria by preventing them from cooperating. The method involves attacking the protective biofilm produced by the whole bacterial colony, rather than the individual bacteria themselves. Because this results in non-resistant bacteria outcompeting their antibiotic resistant neighbors, the strategy does not promote the development of further resistance.
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  • Regional News

Augustine Therapeutics is one of VIB’s latest spinoffs, developing a first-in-class drug for Charcot-Marie-Tooth disease. The company recently announced a seed-funding round of €4.2 million, led by V-Bio Ventures. We spoke to several of the key persons in Augustine about how the startup is tackling the “Valley of Death”: the no-man’s-land between academia and industry where many potential therapies often fail.
Animals have been used throughout history to understand human physiology and to resolve scientific questions related to health and disease. Nowadays, however, both scientists and the public are pushing for better options to animal testing, and so increasing efforts are being put into developing and promoting these alternative methods. Two such initiatives are being spearheaded by the Vrije Universiteit Brussel (VUB): The Innovation Centre for 3R Alternatives (IC-3Rs) and the RE-Place project.
Leuven, Belgium, Feb 20th 2020 - Montis Biosciences announces its launch with €8,4 million in seed financing from an international investor syndicate to investigate interactions between perivascular macrophages and tumor vasculature. The company’s mission is to exploit these cellular interactions with therapeutics to drive and sustain immune reactions against solid tumors.
Inari Agriculture has been awarded the 2020 Newcomer of the Year Trophy by Flanders Investment & Trade (FIT). Inari (US) opened its first foreign R&D branch in Ghent’s biotech valley just over a year ago. Since then, the Belgian team has been hard at work developing plants that can address both growing global food requirements and climate change. They’re approaching the challenge with both the latest genetic techniques and with a fresh perspective on how a business should be run.
Ghent, Belgium, February 10, 2020 - PharmaFluidics NV, an innovative player in the field of analytical chromatography, announces a product range extension into capillary flow rate liquid chromatography (capillary LC).  PharmaFluidics initiates commercial supplies of its new µPAC™ capLC column, bringing unprecedented sensitivity, reproducibility and robustness to a new range of customers worldwide, including the biopharmaceutical industry. PharmaFluidics’ unique high-resolution µPAC™ micro-Chip technology enables separation and detection of individual compounds in complex biological samples such as biopsies, proteome digests, culture media or biopharmaceutical actives, with unmatched precision.
The biotech Bioxodes is using a molecule derived from tick saliva to stop blood clots. The Walloon company is focused on preventing thrombosis during procedures involving medical devices. The current gold-standard anticoagulant can cause unwanted bleeding and side effects; could a molecule derived from ticks really be safer?
With the Belgian biotech landscape blooming, BioVox reached out to some of the investors in our network to see what their predictions are for the coming year. From trends to companies to keep an eye on, here’s their take on 2020!
Researchers have developed a new antibacterial strategy that weakens bacteria by preventing them from cooperating. The method involves attacking the protective biofilm produced by the whole bacterial colony, rather than the individual bacteria themselves. Because this results in non-resistant bacteria outcompeting their antibiotic resistant neighbors, the strategy does not promote the development of further resistance.