The Massimiliano Mazzone group (VIB-KU Leuven) has recently demonstrated that PP2A/B55α promotes the growth of colorectal cancer, by dephosphorylating PHD2 and modifying its enzymatic properties.

Novosanis today announced that it signed an agreement with MDxHealth to supply UrNCollect™, a customized version of the Company’s patented urine collection device called Colli-Pee™. The medical device facilitates accurate sample collection for urine-based tests.

argenx announces its new collaboration with Broteio Pharma. Broteio will perform preclinical research using argenx' SIMPLE antibody platform after which argenx has the exclusive option to license the program for clinical development.

Scientists from Belgium, the UK and the US have identified new processes that form protein “clumps” that are characteristic of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD).

On 15 March Ghent University officially launched a prestigious research project on precision agriculture, led by the Syrian-Belgian top scientist Abdul Mouazen.

Belgian diagnostics producer receives grant from Flemish government to develop microsatellite instability (MSI) test in collaboration with VIB-KULeuven. Not only will the test offer prognosis estimates for colorectal cancer patients, it will potentially be able to indicate whether certain immunotherapeutic approaches are advisable.

EU-LIFE, the alliance of European research centres in life sciences, urges politicians to unequivocally support the ERC by raising its budget in FP9 and endorsing its guiding principles. 

TiGenix, stem cell specialist focused on developing novel therapeutics from its two proprietary platforms of donor-derived expanded adipose derived stem cells (eASC) and donor-derived expanded cardiac stem cells (AlloCSCs), today announced top-line one-year results from the CAREMI clinical trial, an exploratory Phase I/II study of AlloCSCs in acute myocardial infarction (AMI).

Galapagos NV announced two new Phase 2 studies investigating filgotinib in small bowel Crohn's disease as well as in fistulizing Crohn's disease. These studies are being led by filgotinib collaboration partner Gilead Sciences, Inc.

Celyad announced that the U.S. FDA authorized the initiation of the THINK trial in the U.S. THINK evaluates NKR-2 CAR-T cells in seven indications, five solid cancers and two hematological malignancies.

TiGenix NV, an advanced biopharmaceutical company focused on developing and commercializing novel therapeutics from its proprietary platform of allogeneic stem cells, announced today that it has received positive feedback from the U.S. Food and Drug Administration (FDA) on an improved protocol for its global Phase III trial for the treatment of complex perianal fistulas in Crohn's disease patients. This might accelerate the commercialization in the US.

Data from a phase Ib study reveal the Ablynx-developed bi-specific nanobody targeted against IL-17A/F as a promising new therapy to treat psoriasis. Patients in the highest dose group achieved 90% skin clearance and skin biopsies showed complete reversal of disease pathology. A favorable safety and tolerability profile combined with rapid onset of clinical effect makes the nanobody a high-potential therapy.