Biomedical/pharma

Biomedical/pharma, Immunology, Oncology

An excerpt from the BioVox White paper on Cancer Immunotherapy.

Over the years, the perception of inflammatory diseases has changed drastically. The advent of cytokine inhibitors meant great improvement to many patients, especially those suffering from rheumatoid arthritis. However, these treatments remain symptomatic. Together with Janssen Pharmaceutica, world-renowned rheumatologist Lars Klareskog is ready to take the research and treatment of inflammatory joint disease to the next level.

It has long been known that exposure to microbes can play a protective role against the subsequent development of asthma. Researchers from GIGA of the University of Liège provide an explanation and propose to use this discovery to set up a strategy of cell therapy to treat asthma in humans. Their discovery is published in Immunity.

Up to 1 billion people in the world suffer from neurological disorders. Currently, many brain scans are still evaluated by visual inspection. Quantification of different biomarkers in these brain scans can improve diagnosis, patient monitoring and, eventually, patient outcome. The Leuven-based company Icometrix provides software to bring quantification of brain scans into clinical trials and clinical practice. We should stop eye-balling images of brain scans and step into the world of quantitative analysis.

Grail has vowed to change the field of cancer diagnostics via simple blood tests and ctDNA analysis. Their Big Data approach, in which the company will build an atlas of DNA found in the blood, convinced major investors, such as Bill Gates and Jeff Bezos, of the technology’s potential. A whopping $1 billion was gathered in the company’s series B financing round. Yet, do Grail and its technology deserve this huge ticket?

To address the challenges of drug development, solid strategic partnerships are needed. On the Janssen partner day, the company showcased an ongoing partnership with the University of Antwerp in mental health and how this partnership leads to better outcomes.

ADx NeuroSciences might be described best as the Intel of biomarker assays for neuro-degenerative disease. They don’t create complete kits, but their top-notch biomaterials are included in the assays detecting disorders from Alzheimer’s disease to ALS to traumatic brain injury. Over the years, ADx has created an extensive network of partners and by combining knowledge and expertise, these collaborations are leading to innovative markers and valuable new insights in neurodegenerative diseases.
With almost 20 years of experience, Coris BioConcept knows the world of infectious disease diagnostics inside and out. Their straightforward chromatography-based [...]