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Biomedical/pharma

Biomedical/pharma

New advances in the fight against sepsis 

Sepsis is a serious condition where the body responds improperly to an infection. Every 2.8 seconds, someone dies of sepsis globally, yet no direct therapies exist beyond supportive care. Many clinical trials have investigated the role of Tumor Necrosis Factor (TNF) as a potential therapeutic target, but anti-TNF therapy has not proven to be a breakthrough in the sepsis field. Therefore, understanding how TNF triggers this devastating condition could be of help for millions of people worldwide.

4Tissue secures an additional €1.5M in funding and appoints Dr. Katleen Verleysen as independent chair of the board.

Ghent, February 26, 2025 — 4Tissue, a pioneer in biotechnology that is revolutionizing regenerative medicine, has successfully completed an additional €1.5M funding round, consisting of €1M in equity investments and additional grants. This funding will support the further development of the company’s groundbreaking bioresorbable hydrogel technology, which has the potential to significantly improve breast reconstruction and other tissue regeneration applications. This represents an important step forward in the evolution of regenerative medicine, with a particular focus on women’s health.

Belgian innovation in microfluidics: A revolution for diagnostics and cell therapy?  

Microfluidics is a technology that allows researchers to precisely manipulate and control tiny amounts of fluids within networks of channels typically smaller than a human hair. The approach is now achieving the extreme miniaturization necessary to truly enter the ‘lab-on-a-chip’ era, with profound implications for biological research and human health.

AstriVax Therapeutics shoots for the stars with impactful immunotherapies 

In line with its stellar name, AstriVax Therapeutics is a rising star in Belgian biotech. The company launched in 2022 with €30 million – the largest seed round ever raised by a KU Leuven spin-out – and rapidly became a clinical-stage company, using its plug-and-play platform to fast-track development of vaccines and immunotherapies.

ONTOFORCE and Rancho Biosciences Collaborate to Leverage High-Quality Data for Target Identification

Ghent, Belgium, 15 January 2025 – ONTOFORCE, a leader in semantic technology for life sciences, headquartered in Ghent, Belgium, and Rancho Biosciences, the leading data science services company headquartered in San Diego, California, have announced a joint collaboration. This partnership aims to transform high quality data-driven research and drug development, providing scientists with unparalleled insights that drive discovery and innovation in the life sciences.

Galapagos to Unlock Shareholder Value by Declaring its Intent to Separate into Two Publicly Traded Entities 

Galapagos intends to create a new company with approximately €2.45 billion in cash dedicated to building a pipeline of innovative medicines through transformational transactions. Galapagos will gain full global development and commercialization rights to its pipeline, focusing on accelerating cell therapies and building a global, decentralized manufacturing network. Galapagos to implement a strategic reorganization to position the Company for long-term growth and cell therapy leadership in oncology.

What a year…looking back at Benelux biotech in 2024 

As 2025 comes peeking around the corner, we invite you to look back with us at some of the most exciting science topics we covered this year. From advances in women’s health, organoids, and organ-on-a-chip models to the challenges of data science and innovations in animal science and sustainable biotech; let us walk you through the Benelux life sciences landscape of 2024 as we reflect on the vast amount of knowledge and know-how characteristic to this region.

When more screening harms – Shifting prostate cancer care to personalization 

Hot on the heels of Movember, the global movement bringing attention to specific men’s health issues like mental health, prostate, and testicular cancer, let’s take a closer look at the current state of systematic prostate cancer screening and different treatment options available.

Human-first drug discovery: how start-ups can stay ahead of the game 

Every start-up team ponders the all-important question: how to convince investors to fund their idea? Currently, the fundraising landscape is particularly challenging for most early-stage biotech ventures. A fortunate few are raising exorbitant rounds, allowing them to advance their products through preclinical development, but many others are struggling to find the funding they require. In this article, we share our investor perspective on what can help companies to stand out from the crowd, given recent advancements in drug development.

miDiagnostics Secures €30 Million Series D Funding Round Led by Thermo Fisher Scientific to Advance an Innovative Sterility Test and Other Quality Control Tests for use in the BioPharma Industry.

Leuven, Belgium – December 4th, 2024 – miDiagnostics is pleased to announce the completion of a €30 million Series D funding round, led by Thermo Fisher Scientific Inc. (NYSE: TMO), the world leader in serving science. This investment will accelerate the development of a groundbreaking sterility test for batch release and related quality control tests for the BioPharma Industry, utilizing miDiagnostics’ proprietary qPCR technology.

European HealthTech Innovation Needs a Lifeline – Join the Conversation to Drive Change

Ghent, Belgium, 4 December 2024 – European health technology (HealthTech) is at a critical crossroad. Despite groundbreaking research, a thriving startup scene and ambitious talent, the sector struggles to translate innovation into actionable impact. Challenges such as regulatory restrictions, fragmented markets, and funding gaps are slowing progress, while the clock is ticking and other regions of the world are surging ahead.

QbD Group announces acquisition of SciencePharma, strengthening global regulatory and quality expertise

Antwerp, Belgium / Warsaw, Poland – December 4, 2024 – QbD Group and SciencePharma have reached an agreement for QbD Group to acquire SciencePharma. The deal is expected to close by early 2025, pending antitrust clearance.

Refoxy Pharmaceuticals raises €9.1 million to progress its novel FOXO3 therapeutics for Idiopathic Pulmonary Fibrosis.

Investment led by Boehringer Ingelheim Venture Fund, with the participation of new and existing investors, including Apollo Health Ventures, NRW.Venture, and HTGF. ● New financing will accelerate preclinical development of Refoxy’s lead program in IPF as well as the expansion of its platform to additional age-related indications.

3D bioprinting of organs: Futuristic or closer than we think?

A world where we can 3D bioprint organs on demand is creeping ever closer to clinical reality, thanks to Belgian efforts to standardize the biomaterials necessary. Achieving this will have profound consequences for organ transplants, disease modeling, tissue engineering, personalized medicine, and drug discovery. But bioprinting success depends on multidisciplinary collaborations between material scientists, hardware manufacturers, clinicians, and other partners. Recently, these collaborations have reached the stratosphere, with a project to study cardiovascular aging with a heart-on-a-chip… in space!

Cervical cancer – Why some women fall through the cracks of screening 

Cervical cancer is largely curable if detected early enough and yet it remains a leading cause of death in women globally. Why? Although researchers recently made the biggest improvement in cervical cancer treatment in more than 20 years, cutting the risk of death by over 40%, effective and inclusive screening remains crucial for early detection and treatment. However, recent research from Belgium suggests that certain populations of vulnerable women or those with a migration background are falling through the cervical cancer screening cracks.