Environments are scattered with the DNA of the organisms that inhabit them. Analyzing this DNA could shine a spotlight on how our planet’s biodiversity is changing, from studies in the depths of the oceans to the frigid polar regions. From a One Health perspective, biodiversity is crucial to promoting healthy ecosystems and healthy people.
But, while methods that sequence environmental DNA (eDNA) are increasingly powerful in detecting species without direct observation, we need increasingly powerful algorithms to make sense of the complex DNA world around us to truly protect our planet's biodiversity.
The UN has declared antimicrobial resistance (AMR) one of the ten major threats to humanity. In Belgium, AMR is associated with around 8000 deaths per year and contributes to an estimated 4.95 million global human deaths annually, set to almost double by 2050. Unfortunately, there are worryingly few novel antimicrobials in development, and even fewer are currently available to patients with severe infections who need them most. Why?
Drug repurposing describes the process where drugs originally designed for one condition turn out to be highly effective for another. Historically, drug repurposing has often occurred by chance. However, in the era of big data and artificial intelligence, new data-driven opportunities are arising to discover new roles for old medicines and help patients in unexpected ways.
Belgium has long been and remains a global leader in biotech and biopharma, for now at least. The question is: can it maintain that position? Talent and know-how have been key drivers of the country’s success, yet the system supplying both is under pressure. Job openings in the biotech and pharma sectors are growing faster than the educational system can keep up, creating a persistent talent shortage. However, it's not simply a matter of numbers. As the skills needed to support and advance local innovations evolve – AI integration being a prime example – how can we adapt our educational approach while ensuring its stability? This is a question that needs to be answered in order to stay at the forefront of innovation.
From initial discovery to market-ready product, biotech development is a complex multi-phase process, where strategic partnerships, continuous innovation and careful navigation of regulatory landscapes are crucial for long-term success. Despite this complexity (or perhaps because of it), entrepreneurs and VCs seldom take a step back to consider the full trajectory of this journey. In this article, we’ll explore the typical life cycle of a biotech startup, examining the key milestones and hurdles encountered along the way.
Like two sides of the same coin, industry and academia are each aiming to progress science. On their own, they accomplish great results, but only together can they really drive innovation. One way to reap the fruits from this partnership are endowed chairs. By exchanging resources and independence for publicity and innovative insights, both can contribute to a happier and healthier society.
Sepsis is a serious condition where the body responds improperly to an infection. Every 2.8 seconds, someone dies of sepsis globally, yet no direct therapies exist beyond supportive care. Many clinical trials have investigated the role of Tumor Necrosis Factor (TNF) as a potential therapeutic target, but anti-TNF therapy has not proven to be a breakthrough in the sepsis field. Therefore, understanding how TNF triggers this devastating condition could be of help for millions of people worldwide.
Ghent, February 26, 2025 — 4Tissue, a pioneer in biotechnology that is revolutionizing regenerative medicine, has successfully completed an additional €1.5M funding round, consisting of €1M in equity investments and additional grants. This funding will support the further development of the company’s groundbreaking bioresorbable hydrogel technology, which has the potential to significantly improve breast reconstruction and other tissue regeneration applications. This represents an important step forward in the evolution of regenerative medicine, with a particular focus on women’s health.
Microfluidics is a technology that allows researchers to precisely manipulate and control tiny amounts of fluids within networks of channels typically smaller than a human hair. The approach is now achieving the extreme miniaturization necessary to truly enter the ‘lab-on-a-chip’ era, with profound implications for biological research and human health.
Meeting the needs of a growing global population while addressing the clear demand for a more sustainable food supply is challenging but not impossible. Innovative biotechnological tools are constantly being created, and they are increasingly available on the market. However, the industry is in desperate need of support, as EU legislation can act as more of a hurdle than a facilitator, hindering local advancement. flanders.bio is committed to advocating for the sector and highlights the most pressing challenges in their latest policy paper.
Environments are scattered with the DNA of the organisms that inhabit them. Analyzing this DNA could shine a spotlight on how our planet’s biodiversity is changing, from studies in the depths of the oceans to the frigid polar regions. From a One Health perspective, biodiversity is crucial to promoting healthy ecosystems and healthy people.
But, while methods that sequence environmental DNA (eDNA) are increasingly powerful in detecting species without direct observation, we need increasingly powerful algorithms to make sense of the complex DNA world around us to truly protect our planet's biodiversity.
The UN has declared antimicrobial resistance (AMR) one of the ten major threats to humanity. In Belgium, AMR is associated with around 8000 deaths per year and contributes to an estimated 4.95 million global human deaths annually, set to almost double by 2050. Unfortunately, there are worryingly few novel antimicrobials in development, and even fewer are currently available to patients with severe infections who need them most. Why?
Drug repurposing describes the process where drugs originally designed for one condition turn out to be highly effective for another. Historically, drug repurposing has often occurred by chance. However, in the era of big data and artificial intelligence, new data-driven opportunities are arising to discover new roles for old medicines and help patients in unexpected ways.
Belgium has long been and remains a global leader in biotech and biopharma, for now at least. The question is: can it maintain that position? Talent and know-how have been key drivers of the country’s success, yet the system supplying both is under pressure. Job openings in the biotech and pharma sectors are growing faster than the educational system can keep up, creating a persistent talent shortage. However, it's not simply a matter of numbers. As the skills needed to support and advance local innovations evolve – AI integration being a prime example – how can we adapt our educational approach while ensuring its stability? This is a question that needs to be answered in order to stay at the forefront of innovation.
From initial discovery to market-ready product, biotech development is a complex multi-phase process, where strategic partnerships, continuous innovation and careful navigation of regulatory landscapes are crucial for long-term success. Despite this complexity (or perhaps because of it), entrepreneurs and VCs seldom take a step back to consider the full trajectory of this journey. In this article, we’ll explore the typical life cycle of a biotech startup, examining the key milestones and hurdles encountered along the way.
Like two sides of the same coin, industry and academia are each aiming to progress science. On their own, they accomplish great results, but only together can they really drive innovation. One way to reap the fruits from this partnership are endowed chairs. By exchanging resources and independence for publicity and innovative insights, both can contribute to a happier and healthier society.
Sepsis is a serious condition where the body responds improperly to an infection. Every 2.8 seconds, someone dies of sepsis globally, yet no direct therapies exist beyond supportive care. Many clinical trials have investigated the role of Tumor Necrosis Factor (TNF) as a potential therapeutic target, but anti-TNF therapy has not proven to be a breakthrough in the sepsis field. Therefore, understanding how TNF triggers this devastating condition could be of help for millions of people worldwide.
Ghent, February 26, 2025 — 4Tissue, a pioneer in biotechnology that is revolutionizing regenerative medicine, has successfully completed an additional €1.5M funding round, consisting of €1M in equity investments and additional grants. This funding will support the further development of the company’s groundbreaking bioresorbable hydrogel technology, which has the potential to significantly improve breast reconstruction and other tissue regeneration applications. This represents an important step forward in the evolution of regenerative medicine, with a particular focus on women’s health.
Microfluidics is a technology that allows researchers to precisely manipulate and control tiny amounts of fluids within networks of channels typically smaller than a human hair. The approach is now achieving the extreme miniaturization necessary to truly enter the ‘lab-on-a-chip’ era, with profound implications for biological research and human health.
Meeting the needs of a growing global population while addressing the clear demand for a more sustainable food supply is challenging but not impossible. Innovative biotechnological tools are constantly being created, and they are increasingly available on the market. However, the industry is in desperate need of support, as EU legislation can act as more of a hurdle than a facilitator, hindering local advancement. flanders.bio is committed to advocating for the sector and highlights the most pressing challenges in their latest policy paper.