Every year, the Dr. Paul Janssen Award for Biomedical Research is granted to a scientist who embodies the eponymous man’s dedication to his patients and unfailing curiosity and passion for scientific progress. The 2020 winner of this prestigious award is Dr. Lewis Cantley, who discovered the family of PI3K enzymes, thereby increasing our understanding of a wide range of diseases including cancer and diabetes. Nearly 30 years on from this seminal discovery, Dr. Cantley’s research has resulted in more precise cancer therapies that have saved patient lives, making him a true champion of science.
For decades, researchers have been trying to uncover the cause of nodding syndrome, a mysterious and deadly form of epilepsy that only affects children on the African continent. In a collaboration between Belgian and African scientists, researchers from the University of Antwerp have now discovered the root cause of the disease. In a cascade of events, nodding syndrome is triggered by another disease called river blindness, which in turn is caused by parasitic worms spread by blackfly bites. As complicated as it sounds, this is great news for the children, as it means that nodding syndrome can easily be controlled by administering the anti-parasitic drug ivermectin and exterminating blackflies.
While physicians care for their individual patients and are interested in the factors contributing to the individual’s condition, evolutionary biologists investigate the cause of the biological phenomenon, trying to understand for example why a certain disease has developed in a particular species such as our own Homo sapiens. By combining the view of physicians with the view of evolutionary biologists, the field of evolutionary medicine has the potential to improve our understanding of certain diseases and how to prevent them.
Leuven, Belgium, 29 September 2020 - Montis Biosciences, a discovery stage biotech company focused on novel immuno-oncology therapeutics targeting the interactions between perivascular macrophages and the tumor vasculature, has named Karen Zinkewich-Péotti, Ph.D., as its Chief Executive Officer. Dr. Zinkewich-Péotti brings strong R&D leadership experience from both international biopharmaceutical companies and smaller biotech. Over the course of her career she has developed extensive expertise in different therapeutic modalities, including antibodies, antibody-drug conjugates and small molecules.
In July 2020, VIB spin-off ExeVir Bio raised €23 million to advance a llama-derived antibody against COVID-19. The company is based on the work of VIB researchers, who showed that these nanobodies can protect against the coronavirus in lab animals. ExeVir has now announced it will start testing the drug in COVID-19 patients in the coming months. The scientists are aiming to have the therapy ready for widespread use by spring 2021.
In August 2020, V-Bio Ventures announced their investment in Biodol Therapeutics, a French start-up looking to make a difference to people suffering from chronic pain. The company is developing a drug to treat neuropathic pain by addressing the interplay between nerves and the immune system. In a billion-dollar market dominated by ineffective and dangerous painkillers, their unique approach could reduce the suffering of millions.
The German pharmaceutical giant Boehringer Ingelheim has acquired GST, a stem cell specialist based in Belgium. A part of the Anacura Group, GST’s main focus is in animal health, with its main product being a stem cell therapy for injured horses. Despite the acquisition, the company will remain in its labs near Ghent, keeping its research and production rooted in Flemish soil.
Many of our current antiviral, antibacterial and anti-tumour medications are comprised of combinations of two or three active substances, selected on the basis that these combinations slow down emergence of drug resistance. We are currently witnessing a rapid expansion of disease indications for which exploratory drug combos are being tested, as well as of the rationales for combining drugs. In this article, we examine the drivers behind this trend and the inherent caveats and complexities of drug combo development.
V-Bio Ventures, a leading Belgian life sciences VC, invests in Biodol Therapeutics, a French biotech specialized in next-generation chronic pain treatments.
Biodol Therapeutics receives EUR 4.5 million to develop novel FLT3 inhibitors for the treatment of chronic and neuropathic pain, aiming to reach the clinic by early 2023.
Brussels, Belgium / Tokyo, Japan – 27 August 2020 – Newton Biocapital I (“Newton”), an investment company in life sciences, focusing on the treatment and prevention of chronic diseases, with activities in Europe and Japan, has announced its second investment in Japan. Newton invested JPY 480 million (EUR 4 million) – split in two tranches - in J-Pharma Co., Ltd. (“J-Pharma”) as part of a total Series D round of JPY 1.746 billion (EUR 14.55 million) as of July 30, 2020. Newton’s investment in J-Pharma was also its first new investment after it has closed its fund raising at EUR 114 million.
Every year, the Dr. Paul Janssen Award for Biomedical Research is granted to a scientist who embodies the eponymous man’s dedication to his patients and unfailing curiosity and passion for scientific progress. The 2020 winner of this prestigious award is Dr. Lewis Cantley, who discovered the family of PI3K enzymes, thereby increasing our understanding of a wide range of diseases including cancer and diabetes. Nearly 30 years on from this seminal discovery, Dr. Cantley’s research has resulted in more precise cancer therapies that have saved patient lives, making him a true champion of science.
For decades, researchers have been trying to uncover the cause of nodding syndrome, a mysterious and deadly form of epilepsy that only affects children on the African continent. In a collaboration between Belgian and African scientists, researchers from the University of Antwerp have now discovered the root cause of the disease. In a cascade of events, nodding syndrome is triggered by another disease called river blindness, which in turn is caused by parasitic worms spread by blackfly bites. As complicated as it sounds, this is great news for the children, as it means that nodding syndrome can easily be controlled by administering the anti-parasitic drug ivermectin and exterminating blackflies.
While physicians care for their individual patients and are interested in the factors contributing to the individual’s condition, evolutionary biologists investigate the cause of the biological phenomenon, trying to understand for example why a certain disease has developed in a particular species such as our own Homo sapiens. By combining the view of physicians with the view of evolutionary biologists, the field of evolutionary medicine has the potential to improve our understanding of certain diseases and how to prevent them.
Leuven, Belgium, 29 September 2020 - Montis Biosciences, a discovery stage biotech company focused on novel immuno-oncology therapeutics targeting the interactions between perivascular macrophages and the tumor vasculature, has named Karen Zinkewich-Péotti, Ph.D., as its Chief Executive Officer. Dr. Zinkewich-Péotti brings strong R&D leadership experience from both international biopharmaceutical companies and smaller biotech. Over the course of her career she has developed extensive expertise in different therapeutic modalities, including antibodies, antibody-drug conjugates and small molecules.
In July 2020, VIB spin-off ExeVir Bio raised €23 million to advance a llama-derived antibody against COVID-19. The company is based on the work of VIB researchers, who showed that these nanobodies can protect against the coronavirus in lab animals. ExeVir has now announced it will start testing the drug in COVID-19 patients in the coming months. The scientists are aiming to have the therapy ready for widespread use by spring 2021.
In August 2020, V-Bio Ventures announced their investment in Biodol Therapeutics, a French start-up looking to make a difference to people suffering from chronic pain. The company is developing a drug to treat neuropathic pain by addressing the interplay between nerves and the immune system. In a billion-dollar market dominated by ineffective and dangerous painkillers, their unique approach could reduce the suffering of millions.
The German pharmaceutical giant Boehringer Ingelheim has acquired GST, a stem cell specialist based in Belgium. A part of the Anacura Group, GST’s main focus is in animal health, with its main product being a stem cell therapy for injured horses. Despite the acquisition, the company will remain in its labs near Ghent, keeping its research and production rooted in Flemish soil.
Many of our current antiviral, antibacterial and anti-tumour medications are comprised of combinations of two or three active substances, selected on the basis that these combinations slow down emergence of drug resistance. We are currently witnessing a rapid expansion of disease indications for which exploratory drug combos are being tested, as well as of the rationales for combining drugs. In this article, we examine the drivers behind this trend and the inherent caveats and complexities of drug combo development.
V-Bio Ventures, a leading Belgian life sciences VC, invests in Biodol Therapeutics, a French biotech specialized in next-generation chronic pain treatments.
Biodol Therapeutics receives EUR 4.5 million to develop novel FLT3 inhibitors for the treatment of chronic and neuropathic pain, aiming to reach the clinic by early 2023.
Brussels, Belgium / Tokyo, Japan – 27 August 2020 – Newton Biocapital I (“Newton”), an investment company in life sciences, focusing on the treatment and prevention of chronic diseases, with activities in Europe and Japan, has announced its second investment in Japan. Newton invested JPY 480 million (EUR 4 million) – split in two tranches - in J-Pharma Co., Ltd. (“J-Pharma”) as part of a total Series D round of JPY 1.746 billion (EUR 14.55 million) as of July 30, 2020. Newton’s investment in J-Pharma was also its first new investment after it has closed its fund raising at EUR 114 million.