A bridge from East to West: linking Chinese and European biotech

December 1, 2020 Sponsored Quality by Design - Business & Communications

There are two main reasons why a European company might want to establish official links with a Chinese investor: funding, and access to the second largest healthcare market in the world. But don’t go rushing in blind!

By Amy LeBlanc

In November 2019, a large delegation of Belgian companies accompanied by Princess Astrid of Belgium undertook an economic mission to China. Coupled with a China Healthcare Summit organized by BioCentury, the purpose was to foster the development of economic and trade relations. After the huge success of last year’s mission, a virtual event took place again in November 2020.

Read this previous BioVox article to learn about the 2019 economic mission success stories.

Strengthening ties with China is something an increasing number of European companies are interested in. For numerous reasons, European companies are starting to turn their gaze to the East just as Chinese investors are looking to the West for opportunities. This is particularly true in high-tech industries such as biotech and the life sciences.

At the forefront of this tentative outreach between Europe and Asia we find a company called Agio Capital & Business Solutions which operates as an advisory firm. Their main mission is to connect European companies with suitable investors and partners, with a strong focus on the Chinese market.

There is a big need for all kinds of medical equipment, services and medicine, and the Chinese players cannot always provide the right quality yet. So, they have to rely on Western innovation. – Sven Agten, Agio Capital & Business Solutions

BioVox interviewed Henk Joos and Sven Agten to find out what China has to offer and how a life sciences company should go about setting up shop in China. Henk Joos is one of the company´s directors and former managing director of flanders.bio. Sven Agten is a Belgian turned Chinese businessman and is living in China already for 16 years, right in the middle of the Shanghai healthcare innovation ecosystem.

China: an attractive healthcare market

In the past few decades, the Chinese economy has grown astronomically. This boom has also been reflected in the healthcare market. From a commercial perspective, China is very attractive for a company involved in the life sciences. The Chinese healthcare market is currently the second largest in the world (only surpassed by the US). Agten explained why it is expected to expand even more:

“There are now 300 million Chinese middle-class people who can afford both healthcare and luxury products. That’s a huge market for Western companies. The Chinese middle-class have a lot of money and they’re getting richer every day.

China also has a lot of issues with pollution, food scandals and changing lifestyles. These are leading to an increase in cancer and obesity-related diseases. The ageing population is also an enormous factor. There is a big need for all kinds of medical equipment, services and medicine, and the Chinese players cannot always provide the right quality yet. So, they have to rely on Western innovation. We believe the COVID-19 crisis, where China recovered earlier and more successfully than the West, will only expedite this trend.”

Read this previous BioVox article to learn more about the evolution of Chinese biotech.

Looking to Europe for innovation

The need for innovative healthcare solutions, backed by the ability to pay for them, has been the driving force behind Chinese investment in the sector. However, the Chinese life sciences industry is still lagging behind the ecosystem in the US and Europe. Joos elaborates:

“When we look at the life sciences landscape, and the research that is being done, we can clearly see that China is catching up rapidly. But they don’t have yet the network and experience in place to consistently translate that research into successful companies.

In Flanders, we know how difficult translation is: we have been quite successful, but it essentially took 45 years for us to start building successful companies like Galapagos, argenx and Ablynx. It requires a combination of talent, managerial expertise and experienced investors.

The Chinese are currently repatriating a lot of their talent from the US and Europe, but they are still in early development. Therefore, there is currently a big desire to bring technology and management expertise from abroad on board. We believe that the economic and health impact of COVID 19 will impact this trend even more. The global health crisis resulted in an experience-based performance of the Chinese health system but emphasized the complementary needs in China for top technology. The fact that China is coming out of this crisis relatively unharmed will expedite the healthcare sector conversion in China.”

We are at the right time and the right place: for European companies that want to enter the Chinese market, the critical timeframe will be the following 10-15 years. – Henk Joos, Agio Capital & Business Solutions

With the US and China currently locked in a trade war, the Chinese are actively being blocked from working with US companies. With no end in sight to this technology cold war, China is turning its gaze towards Europe, which has opened up a window of opportunity for European companies. Joos emphasized the urgency of this chance:

“It’s very clear that the US and China are decoupling in any way possible. Cut off from their US networks and opportunities, Chinese investors are becoming increasingly interested in what Europe has to offer.”

Don’t go rushing in blind

It is clear that Chinese investors have a lot of capital available. The average fund size is now $765 million. In 2018, China’s VC investments into life sciences exceeded even the US. Beyond the money, working with Chinese investors or partners also opens doors to the Chinese market. Without ties to the local network, success in China can be devilishly hard to attain.

It’s still critical for a Western company to find a trustworthy Chinese partner who will fight for your IP and regulatory approvals. But the government has clearly taken a number of measures… to make the system more robust. – Henk Joos, Agio Capital & Business Solutions

As with any endeavor, however, it is critical to do your homework and come prepared. When considering working with Chinese funds, people have a lot of questions and concerns. One of the main reasons for reservation is often the threat of IP theft and licensing issues. Agten acknowledged that this used to be a real problem:

“Up until 5-10 years ago, Chinese companies didn’t have a lot of IP. To compensate, they would sometimes steal IP from Western companies. This is where they got their bad reputation from.

In the past decade, things have changed dramatically. In 2018, 43% of all the global patent applications came from China. Chinese companies are now at the point where they have developed so much IP that they need to protect their own assets. The Chinese government has acknowledged this and have made vast improvements to their IP laws.

International Chinese investors are also a lot more vigilant: they invest in listed companies and cannot afford any controversy. They absolutely cannot be caught up in IP theft or licensing issues; they have a reputation to protect.”

Read this previous BioVox article for a European fund perspective on Chinese investors.

Does this mean that everything has been resolved? Joos replied:

“Is everything rosy? No: it’s still a work in progress. Which is why it’s still critical for a Western company to find a trustworthy Chinese partner who will fight for their IP and regulatory approvals.

But the government has clearly taken a number of measures, with IP firms and the China FDA (now the National Medical Products Administration (NMPA)), to make the system more robust. It is rapidly approaching a polished state.”

Prepare for the future

It will be interesting to see how many new deals come out of the 2020 digital China Healthcare Summit. Joos and Agten and other colleagues of Agio Capital & Business Solutions attended, along with significantly large contingent of interested European life sciences companies. According to them, the next few years are ideal for European companies wanting to access the Chinese market.

Current events are creating opportunities for European companies to focus not only on two markets, Europe and the US, but on three: Europe, the US and China. – Sven Agten, Agio Capital & Business Solutions

Joos and Agten both cautioned not to rush in blind though. As with any opportunity, you need to do your research. According to them, the number one thing is to get your foot in the door and establish links with the existing Chinese network. Agten left us with the following advice:

“As a company, you have to build for the long term. Current events are creating an opportunity for European companies to focus not only on two markets, Europe and the US, but on three: Europe, the US and China. The time is ripe now.”

This article was sponsored by Agio Capital & Business Solutions. The article was originally published in October 2019 and was updated in December 2020.

Avatar photo
Quality by Design - Business & Communications

Quality by Design (QbD) - Business & Communications is a team of expert strategists, scientists, communicators, and creatives. Whether you're a part of an innovative startup or an established player, our unique approach will ensure that your company has the best chance of being seen and understood by your target audience: prospects, clients, investors, partners, and more. We don’t just consult; we also help you implement. We share articles on BioVox providing insight into new and established players in the Benelux Life Science ecosystem, from innovations and research breakthroughs through to finance and industry trends.

All posts

Subscribe to the BioVox newsletter