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Dualyx: restoring the body’s balance in autoimmune diseases

Belgian start-up Dualyx is developing a novel approach with the potential to treat a wide range of autoimmune disorders. The method uses llama-derived antibodies to flip a master switch and create regulatory T cells, which help restore order to overzealous immune systems.

Drug development trends: from common to orphan indications… and back again?

Over the past few decades, pharma has gradually shifted its target patient focus for newly launched drugs from large to niche populations. What has caused this trend, and is the pendulum of drug development swinging back again?

VIB: a new focus on data science with Christine Durinx at the helm

Christine Durinx has been appointed as the new co-Managing Director of the world-class life sciences research institute VIB. Taking over from Jo Bury, Durinx joins VIB’s other co-Managing Director Jérôme Van Biervliet in ushering in a new era of discoveries increasingly driven by data science.

Antimicrobial Resistance – the hidden killer we’re ignoring

Antimicrobial Resistance has become an enormous challenge for global health, yet remains largely ignored by companies. As this deadly race worsens, we urgently need to address the huge mismatch between the need and incentive for developing new antimicrobial drugs.

RE-Place project: Reducing animal research through alternative methods

If scientists could stop animal testing, most would do so immediately. So why is it taking so long to develop alternatives to animal testing? And what are we doing to speed up the process?

When should a biotech hire a CFO?

Many argue that young companies have little need for a Chief Financial Officer (CFO). They would say that CFOs are unnecessary and costly add-ons early on when a business’ financial needs can be satisfied through outsourcing or by a more junior member of staff. However a CFO brings a deeper and more strategic financial perspective which can help a company outgrow the competition. So, is delaying CFO recruitment a sensible budgetary decision or an expensive mistake?

Economic Success: infinite growth is only possible in a diverse ecosystem

In recent public discussions on economic progress, people have been asking: is infinite growth really the best way to measure economic success? With a background in biology, having entered the investment world in the year 2000, Christina Takke found this an intriguing question best viewed through the metaphor of life in a test tube versus a real ecosystem.

Belgium: The Health & Biotech Valley of Today and Tomorrow

As part of the ‘Health & Biotech Valley of Tomorrow’ initiative, the Belgian government recently signed a charter together with stakeholders from academia and industry, pledging to cement Belgium’s status as a biotech powerhouse in the next 10 to 20 years. Over the next few months, working groups will translate recommendations of a consultancy report into a concrete strategic plan for the future of the country. Amongst other topics, experts will evaluate ways to encourage more collaboration, provide financial stimuli, and make better use of health data.

Long COVID: what it means for the life sciences industry and other chronic conditions

Long COVID is a less talked-about aspect of the COVID-19 pandemic, yet its impact on society is already profound. Although this problem is still largely flying under the radar of the life sciences industry, a couple of first movers have already initiated clinical programs to address the condition. If more companies move into this space, long COVID may prove a catalyst for R&D in other related and underserved indications, like chronic fatigue syndrome.

Unlocking doors: Key considerations for start-ups during Discovery and Development

Mark Hicken is Vice President of Strategy for Europe, Middle East and Africa (EMEA) at the Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen). With more than 20 years of experience in the company, Mark leads a cross-functional team that drives Janssen’s continued growth across the region, in close collaboration with the local operating companies. On the 28th of October, Mark presented a talk during an online event hosted by Johnson & Johnson Innovation – JLABS (JLABS) ‘Start at the End: Thinking Commercial during Discovery and Development’ (recording available here). Following the webinar, Mark shared some additional insights and advice with us.

Confo-dently into the future!

Confo Therapeutics is a rising star in Belgium, featured on several local and international lists of up-and-coming biotechs. The company, launched in 2015 as a spin-off of the Vrije Universiteit Brussel (VUB) and VIB, is now taking the big step from the preclinical to the clinical stage with a GPCR drug for neuropathic pain.

Belgium has all the ingredients to be number one for real-world data in healthcare

Belgium is home to one of the world’s strongest health clusters and has long been ranked as the best country in the EU for clinical trials. However, if Belgium is to maintain this attractive clinical trial environment – and its quality healthcare system – the country needs to improve its position regarding the reuse of health data for research. BioVox spoke with Ingrid Maes from Inovigate about an upcoming report on Belgium’s real-world data initiatives and legislation, and how the country compares with the rest of Europe.

Knowledge for Growth insights on sharing health data

Knowledge for Growth is Belgium’s largest life sciences conference, and with a mix of thought leaders from across the ecosystem, always has a finger on the pulse of current topics. This year, the event focused heavily on data science, with a range of keynote talks and sessions dedicated to the important topic. One of the afternoon panels in particular, Understanding Data, held a lot of insights from Liesbet Peeters (Prof. Biomedical Data Sciences at Hasselt University) and Bart Vannieuwenhuyse (Data Sciences Lead at Janssen Benelux Campus).

New GMOs on the horizon: say ‘cheese’!

To meet the challenges of climate change and global food demand, more VCs are investing in AgTech companies. A lot of these companies are using genetic modification to create better plant-based alternatives for animal products. One US company, Nobell Foods, is even developing casein-producing soybean plants that can be used to make plant-based cheese that tastes and melts like the real deal.

Maccabi safely unlocks a treasure trove of health data for research insights

Progress in the use of patient healthcare data is going slow for most countries, but some are racing ahead and setting the bar high. In Israel, the healthcare provider Maccabi has developed a system where researchers can access decades of medical records without compromising patient privacy. This incredible trove of medical data has given rise to groundbreaking academic and industry research, improving the lives of people around the world.