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Biogen’s controversial Alzheimer’s drug approved by the FDA – what now?

It has been three months since the much-discussed FDA approval of Biogen’s Aduhelm, a treatment for Alzheimer’s Disease. The drug has been celebrated by some as a breakthrough for Alzheimer’s patients, but others remain highly sceptical or even openly opposed to the FDA decision. What has caused the furor? And what will this approval mean for other biotech companies developing new drugs for neurodegenerative diseases (and for the VCs backing them)?

Why keeping up with data science matters for our health

Data without science is nothing; just 1s and 0s, floating around a cloud waiting for someone to make sense of them. Data science is the process of extracting value from data, using advanced analytics tools. Enormous amounts of health information are being gathered every second, and we are rapidly getting better at decoding it: turning bytes into insights that can be used to improve the lives of patients. But the pace, methods and ethics of data science adoption varies dramatically between countries and regions. Why should we care about keeping up?

Cancer diagnosis and therapy in one: Precirix tackles tumors with camelid antibodies

A new drug that can identify tumors, trace metastases, and treat cancer – all in one? Belgian start-up Precirix is aiming high with its lead compound – a precision radiopharmaceutical using camelid antibodies to bind to, and irradiate, cancer cells.

Moderna: from secretive platform company to vaccine superstar

Moderna Therapeutics has never really been a typical biotech. Sure, nowadays it is world famous thanks to its COVID-19 vaccine, which has resulted in an $80 billion market cap and projected sales of $18.4 billion for 2021. But the path to success has not been that of a standard biotech’s journey. Through ups and downs, controversies and triumphs, here’s the fascinating story behind the rise of Moderna and the creation of its COVID-19 vaccine.

Friend or foe: building a healthy relationship with your board

CEOs of start-ups face many challenges. Among many tasks, they have to set up the organization, write the business plan, build an effective management team and, of course, attract finance. How concerned should they be with the composition of the board? And what can CEOs do to ensure that the board helps rather than hinders their company?

SciMingo: bringing science to the center stage

The world needs more quality science communication. The value to society is evident, as clear communication is key to science-based policy and incentivizing funding for innovation. But does science communication help the individual researchers themselves? And what can be done to encourage public outreach?

To fund or not to fund: the psychology of investment decisions

Much has been written about the psychology of decision making and how venture capitalists choose which companies they want to fund. Although due diligence is an important part of the process, first impressions and emotions play a huge role in reaching that stage. Diverse teams are vital to making sure that gut reactions aren’t driving poor investment choices in VC funds.

AgomAb’s journey of growth in regenerative medicine

Ghent-based AgomAb Therapeutics recently raised a Series B of $74 million, the largest round ever for a Belgian biotech in pre-clinical phase. Based on argenx’ technology, the company is developing HGF-mimetic antibodies for regenerative medicine. AgomAb has come a long way since it’s foundation in 2017 and has been pegged by many as one of the future stars of Belgian biotech.

Soy in 1000 gardens: citizen science project to map soil microbes in Flanders

Good science takes many hands. In the case of a new citizen science project by VIB, UGent, ILVO, KU Leuven, the hands they were after were green-thumbed individuals in Flanders. The institutes have recruited gardeners to plant soybeans, in the hope of identifying microbial species in soils across Flanders that promote the growth of the vital crop. The ultimate aim is to increase sustainable soy production in the region.

Wallonia to invest in plant-based proteins as meat substitutes

The Walloon region is taking major steps towards becoming an important player in the business of plant-based proteins. In the next few months, two of the region’s public investment funds, Sogepa and SRIW, plan to establish a start-up company in this booming field. In the long term, the goal is to create an entire ecosystem around the use of plant proteins as meat replacements, benefiting the economy, health and sustainability of the whole area.

V-Bio Ventures: a fresh fund with a difference

V-Bio Ventures recently announced their second fund, with the first closing already totaling 78 million euros [final close at 110 million euros - Ed.]. As a VC fund with a focus on early-stage life sciences companies, V-Bio will be using Fund 2 to continue supporting European start-ups working on effective healthcare or sustainable agriculture solutions. In this interview, co-founders Christina Takke and Willem Broekaert, along with new Managing Partner Shelley Margetson, share some success stories from V-Bio’s first five years and how they plan to create value for both investors and society in the future.

New VIB incubator gives agbiotech start-ups a chance to flourish

In mid-2021, research institute VIB will open its brand-new agbiotech incubator. The new complex will provide entrepreneurs with access to high-tech facilities to work on sustainable agricultural innovations, like solutions to make plants more resistant to drought. The incubator will be housed in the former CropDesign site of multinational BASF in Nevele, Belgium.

How to build the right team for start-up success

One of the key ingredients to start-up success is a stellar management team. Attracting (and retaining) the right kind of talent is a challenge though, especially when trying to balance the skills and personalities of different individuals. Getting this balance right is key to a well-rounded and cohesive team that will let a company grow into its full potential. Here is our advice on some important factors to bear in mind when building a life sciences management team.

Decades-old discoveries cause paradigm shifts in modern medicine

Complete paradigm shifts in medicine are rare, but there have nevertheless been several major examples in the past hundred years. Treatments and approaches that seemed set in stone one decade can easily seem silly the next, as new information about the disease or underlying biology comes to light. Hindsight grants us clarity, but sometimes the factors that lead us down a particular treatment path can be as arbitrary as a feud between colleagues. Might there be paradigm shifts looming in oncology, neurology and more, triggered by a return to previous treatments?

A life-changing discovery: CRISPR scientists awarded the 2020 Nobel Prize in Chemistry

After several years of nominations, Emmanuelle Charpentier and Jennifer Doudna have finally been awarded the 2020 Nobel Prize in Chemistry for their development of CRISPR/Cas genetic editing. These ‘genetic scissors’ can be used to can change the DNA of animals, plants and microorganisms with unprecedented precision. CRISPR technology has already had a revolutionary impact on the life sciences, but the technique and the Nobel prize itself aren’t without controversy.