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Biomedical/pharma

Agrofood, Biomedical/pharma, Environment/sustainability, Infectious disease

VC opportunities for impact in the face of climate disaster

Venture capitalists have a vital role to play in guiding our planet’s future. By investing in technological advances that remediate environmental ruination, enable adaptation to new conditions, and heal challenging diseases, VC funds can help improve the world while also benefiting their bottom line. But there is an even bolder approach available to VCs who really want to do good: influencing governments by earmarking funds for advocacy groups.

The inspiring potential of gene therapy in neurology

Dr. Monica Bennett is Head of Gene Therapy Unit at Novartis, the company behind the world’s only gene therapy approved for a neurological indication. Zolgensma treats children with spinal muscular atrophy (SMA), a genetic condition where infants with the most severe type rarely survive past their first few years of life. We spoke to Dr. Bennett about her experience working with SMA kids and their families, and the inspiring potential of gene therapy in other neurological diseases.

V-Bio Ventures portfolio company Biodol Therapeutics nominates its first preclinical candidate as a next-generation therapy for neuropathic pain

KU Leuven spin-off AstriVax raises € 30 million to build vaccine platform

Augustine Therapeutics: time to reverse nerve damage in patients undergoing chemotherapy or with Charcot-Marie-Tooth disease

Augustine Therapeutics is a VIB and KU Leuven spin-off developing innovative therapies for peripheral and central nervous system disorders. The company initially focused on treating Charcot-Marie-Tooth disease, and recently added a major indication to their lead program after finding strong evidence that their drug candidate can also reverse nerve damage caused by chemotherapy. Augustine Therapeutics aims to initiate clinical trials by 2024.

Bacterial biofilms: cooperative bugs cling to food surfaces even after cleaning

Current cleaning and disinfection practices in food industries are insufficient to destroy unwanted bacteria lurking on surfaces, according to recent Belgian research. Cooperation between diverse types of bacteria makes them stronger and more resilient, causing huge damage in terms of food spoilage, recalls, and health issues. Understanding the development of these microbial communities and their underlying cooperation is vital for assuring food safety, and may lead to developing better forms of biocontrol.

Gene therapy pioneer Dr. Katherine High on the past and future of the field

Dr. Katherine High is one of gene therapy’s pioneers, who has contributed to a long list of firsts in the field. As President of Spark Therapeutics, Dr. High led the team that developed Luxturna ­– the first FDA-approved gene therapy in the world and the first to be approved in both the US and Europe. Prior to that, her trailblazing clinical work with adeno-associated viral (AAV) vectors helped paved the way for many subsequent gene therapies. Today, Dr. High continues her cutting-edge work as President of Therapeutics at gene therapy company AskBio, a wholly owned subsidiary of Bayer AG. We spoke with Dr. High about the evolution of this fascinating field, which has the potential to provide transformational therapies for so many people with otherwise untreatable genetic diseases.

Belgian stakeholders unite to strive for data science integration in healthcare

Data science is booming, including in the healthcare sector. However, in order to extract insights and benefits from our health data, we first have to build a solid system for structural data processing and management. To frame the needs for healthcare data reuse in Belgium, Inovigate has united stakeholders and summarized their recommendations in two white papers.

Dr. Ajit Shetty: breaking down barriers in the life sciences

A veteran of the life sciences industry, Dr. Ajit Shetty continues to have a huge impact on the ecosystem both in Belgium and abroad. Several years after his retirement from top positions in Janssen Pharmaceutica & Johnson and Johnson (as Chair and previously as Managing Director), Shetty is still actively involved in the industry. Awarded the title of Baron by King Albert II of Belgium in 2008 for his services to the sector, and the recipient of Trends ‘Manager of the Year 2004’ and the Life-Time Achievement Award by India (his country of birth), Shetty is a living legend who is still busy shaping the world’s future.

Obesity weighs heavy on healthcare and human lives

Being overweight is not only bad for one’s health – it also costs society a lot of money. Every year, the Belgian government loses at least 4.5 billion euros due to the direct and indirect costs linked to excessive weight and obesity. As with COVID-19, this issue needs to be tackled as a public health concern: the responsibility of both individuals and policymakers.

Indigo develops device to make light work of diabetes management

Ghent-based Indigo aims to make a huge difference to the quality of life of people with diabetes. The company is developing a device to render the monitoring of blood sugar levels painless and invisible, a major improvement compared to the tools available today. The innovative technology is based on spectroscopy – using light to measure glucose levels through the skin.

Dualyx: restoring the body’s balance in autoimmune diseases

Belgian start-up Dualyx is developing a novel approach with the potential to treat a wide range of autoimmune disorders. The method uses llama-derived antibodies to flip a master switch and create regulatory T cells, which help restore order to overzealous immune systems.

Rejuvenate Biomed appoints life sciences leader Dr. Ajit Shetty as Chair of the Board of Directors to help guide international ambitions

Augustine Therapeutics appoints Gerhard Koenig as Chairman of the Board, forms Clinical Advisory Board, and broadens therapeutic indications

Leuven, Belgium, 10 May 2022 – Augustine Therapeutics, a biotech company developing novel therapies for neuromuscular and neurodegenerative disorders, appoints Gerhard Koenig as Chairman of the Board. The company also expands the Scientific Advisory Board with clinical experts to support broader therapeutic applications, exploring the potential of novel HDAC6 inhibitors in Charcot-Marie-Tooth disease (CMT), and now also in other indications such as chemotherapy-induced peripheral neuropathy (CIPN), and amyotrophic lateral sclerosis (ALS).

miDiagnostics launches its CE-IVD certified ultra-fast COVID-19 PCR test