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V-Bio Ventures

We are a life sciences fund investing throughout Europe in start-up and early-stage companies with high growth potential. Our articles cover investment-related topics in life sciences, including innovation trends, the latest business themes and exciting updates on our portfolio companies.
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Picture of V-Bio Ventures

V-Bio Ventures

We are a life sciences fund investing throughout Europe in start-up and early-stage companies with high growth potential. Our articles cover investment-related topics in life sciences, including innovation trends, the latest business themes and exciting updates on our portfolio companies.
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Fake it till you fund it?

Silicon Valley investment gurus have long promoted the idea that startups should ‘fake it till you make it’ to become successful. The infamous fall of Theranos is a perfect showcase of how this attitude can turn into a disaster. We take a closer look at this philosophy of exaggeration and weigh up the merits of ‘fact vs. fiction’ when life sciences entrepreneurs are dealing with potential investors.

V-Bio Ventures portfolio company Dualyx raises €40 million to progress Treg therapies for autoimmune diseases into the clinic

Corteria: a new strategy and approach to treating heart failure

Corteria Pharmaceuticals is developing transformative therapies for heart failure subpopulations most likely to benefit from the company’s novel cardiorenal treatments. The company was founded in 2021 by Sanofi’s former head of cardiovascular research, Philip Janiak, and Marie-Laure Ozoux, former cardiovascular project leader at Sanofi.

Are we at the end of the biotech boom cycle?

Bankruptcy, closures, and layoffs – oh my! But it’s not all doom and gloom for the biotech boom. Innovation is still in demand, and although the VC landscape is changing, companies are still able to find funds.

V-Bio Ventures portfolio company Confo Therapeutics Announces Global Licensing Agreement with Lilly for Peripheral Pain Candidate, CFTX-1554

The hype cycle in life sciences investments: go with the flow or fight the current?

Everyone in the investment business is familiar with the phenomenon of technology hypes. These trends tend to come and go like inevitable tidal waves, and it’s easy to get swept up in the furious rush. But should you go with the flow, or are you better off swimming against the tide of technology trends?

Coave Therapeutics: redecorating viral vectors for improved gene therapies

Coave Therapeutics is a French biotech developing gene therapies for neurodegenerative and ocular diseases. The company has developed a technology platform that can be used to redecorate the outer surface of viruses, creating gene therapy vectors that are better at accurately delivering healthy genes to the right target cells, including neurons in the deep brain tissue. By combining this vector technology with transgenes restoring natural cell cleaning pathways, the company has created a pipeline of therapies for both genetically and non-genetically defined neurodegenerative diseases, such as Parkinson’s Disease, Multiple System Atrophy (MSA), and Amyotrophic Lateral Sclerosis (ALS).

Why diversity matters in management teams, and how to achieve it

The biotech industry is suffering from a serious talent shortage, with start-ups in particular having an increasingly hard time filling C-level positions. Yet despite this difficulty, many job searches are failing to look beyond the industry’s stereotypical candidate, throwing their hands up in despair when the typical white middle-aged man can’t be found to fill the role. In broadening the search to include more diverse candidates – including women and people with different ethnic backgrounds – we will not only help to address the talent shortage but also strengthen the start-ups themselves. So how can a company build and maintain a more diverse management team?

Cancer vaccines: not only treating tumors, but preventing them too

The COVID-19 pandemic has brought vaccines back into the drug development spotlight, and mRNA vaccines are stealing the show with sales of USD 54.4 billion in 2021 alone. Few know that the developers of the mRNA COVID-19 vaccines actually drew upon years of experience attempting to develop cancer vaccines. This approach goes back several decades, and although the field has to date seen limited success, it has nevertheless witnessed a renewed interests in recent years. We examine the latest trends in cancer vaccine development, and where the opportunities lie for the future of the industry.

We need more food and agtech start-ups – and we need them now!

How are we going to feed an expected 10 billion people by 2050 in a sustainable way? It is a daunting task. Our climate is changing, and a combination of environmental and economic factors are already resulting in widespread food shortages. There is no simple solution to this problem, but innovation in the food and agtech sector will help alleviate the burden. To make this possible, stakeholders – including researchers, entrepreneurs, investors, and governments – need to make agrifood innovation a priority immediately.

V-Bio Ventures leads Sibylla Biotech’s EUR 23 million Series A to advance a novel therapeutic approach for undruggable diseases

VC opportunities for impact in the face of climate disaster

Venture capitalists have a vital role to play in guiding our planet’s future. By investing in technological advances that remediate environmental ruination, enable adaptation to new conditions, and heal challenging diseases, VC funds can help improve the world while also benefiting their bottom line. But there is an even bolder approach available to VCs who really want to do good: influencing governments by earmarking funds for advocacy groups.

V-Bio Ventures portfolio company Biodol Therapeutics nominates its first preclinical candidate as a next-generation therapy for neuropathic pain

KU Leuven spin-off AstriVax raises € 30 million to build vaccine platform

Augustine Therapeutics: time to reverse nerve damage in patients undergoing chemotherapy or with Charcot-Marie-Tooth disease

Augustine Therapeutics is a VIB and KU Leuven spin-off developing innovative therapies for peripheral and central nervous system disorders. The company initially focused on treating Charcot-Marie-Tooth disease, and recently added a major indication to their lead program after finding strong evidence that their drug candidate can also reverse nerve damage caused by chemotherapy. Augustine Therapeutics aims to initiate clinical trials by 2024.