Clinical drug development is a challenging endeavor, but help is at hand! From trial site selection, to patient recruitment, to endpoint characterization – data science integration can help to overcome bottlenecks and improve efficiency in clinical development by generating unique insights to help guide study design and operations. For this strategy to be used to its full potential in Belgium, local partners should optimize data governance and quality, and improve collaboration. This would help the country maintain its status as a leading location for clinical trials.