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Infectious disease

Agrofood, Biomedical/pharma, Environment/sustainability, Food technology, Healthcare technology, Infectious disease, Microbial systems and fermentation, Personal/public health, Plant science, Public health, Veterinary science

The benefits of One Health in Flanders

Biovia is Europe’s first industry-led One Health innovation cluster—uniting medical biotech, medtech, digital health, agtech and industrial biotech to advance human and planetary health. Katrien Lorré explains how this unified approach benefits companies by unlocking opportunities and fostering a better environment for health innovation.

Belgian research pushes the boundaries of coronavirus treatment to prevent the next pandemic

According to the World Health Organization (WHO) SARS-CoV-2 is experiencing a resurgence, with the risk of future outbreaks from emerging variants remaining substantial. To stay ahead of the curve, continued investment in both preventative measures and novel therapies is vital. Groundbreaking Belgian research is leading the way with high-potential compounds targeting SARS-CoV-2, offering a promising new avenue for treatment and pandemic preparedness.

When ignorance isn’t bliss – more knowledge is crucial to combat deadly Candida auris fungus 

Infectious diseases are commonly associated with bacteria and viruses. However, fungi should also be added to this list as there is growing concern that antifungal resistance could be the next global challenge. Moreover, because fungi are eukaryotic like humans, developing targeted treatments without causing toxicity to the host presents a significant challenge. The World Health Organization has recently published its first list of health-threatening fungi. This list aims to promote research to enhance the global response to fungal infections and the growing issue of antifungal resistance. One ‘high-priority’ fungus in particular, Candida auris, has mycologists holding their breath due to its rapid global spread and multidrug resistance.

Fighting antimicrobial resistance: How public and private investment is essential 

The UN has declared antimicrobial resistance (AMR) one of the ten major threats to humanity. In Belgium, AMR is associated with around 8000 deaths per year and contributes to an estimated 4.95 million global human deaths annually, set to almost double by 2050. Unfortunately, there are worryingly few novel antimicrobials in development, and even fewer are currently available to patients with severe infections who need them most. Why?

AstriVax Therapeutics shoots for the stars with impactful immunotherapies 

In line with its stellar name, AstriVax Therapeutics is a rising star in Belgian biotech. The company launched in 2022 with €30 million – the largest seed round ever raised by a KU Leuven spin-out – and rapidly became a clinical-stage company, using its plug-and-play platform to fast-track development of vaccines and immunotherapies.

This vagina-on-chip model holds the potential to advance yeast infection research

While a vast majority of women experience vaginal yeast infections, research has fallen short in providing an effective treatment approach. However, hope has emerged recently with the development of new model systems that allow exploration of the complex vaginal environment. Organ-on-chip models enable researchers to examine the interactions between human cells and microbes in a more accurate manner, offering the potential for the development of new therapies.

Bridging the immunity gap: improving animal welfare without antibiotics

Antibiotic resistance is a major concern for humans and animals. Increasing pressure to move away from antibiotics has created space for new solutions for disease management. Animab’s oral monoclonal antibody platform is a promising alternative, effectively guarding against infection during a vulnerable period in an animal’s development.

Obulytix is developing a revolutionary solution for antibiotic resistance

Obulytix, a spin-off based on research results from Ghent University and KU Leuven, has built a platform that creates new ways to tackle bacterial infections. The innovative, phage lysin-based platform – leveraging the power of artificial intelligence – attracted a significant four-million-euro investment from Boehringer Ingelheim Venture Fund, Qbic, and Gemma Frisius Fund.

From multiple pills per day to one treatment per month: progress in HIV medication made possible by pharma collaborations

Unprecedented collaborations between different pharmaceutical companies have resulted in extraordinary progress for HIV patients over the past four decades. From the first ever treatments, to single pills and now even long-acting injections, treatment options have come a long way. In this interview, Dr. Theresa Pattery (Head of Disease Management Programs at Janssen Pharmaceutica) tells us of this long journey and talks about the role of drones and phones in the world-wide fight against HIV.

VC opportunities for impact in the face of climate disaster

Venture capitalists have a vital role to play in guiding our planet’s future. By investing in technological advances that remediate environmental ruination, enable adaptation to new conditions, and heal challenging diseases, VC funds can help improve the world while also benefiting their bottom line. But there is an even bolder approach available to VCs who really want to do good: influencing governments by earmarking funds for advocacy groups.

KU Leuven spin-off AstriVax raises € 30 million to build vaccine platform

Bacterial biofilms: cooperative bugs cling to food surfaces even after cleaning

Current cleaning and disinfection practices in food industries are insufficient to destroy unwanted bacteria lurking on surfaces, according to recent Belgian research. Cooperation between diverse types of bacteria makes them stronger and more resilient, causing huge damage in terms of food spoilage, recalls, and health issues. Understanding the development of these microbial communities and their underlying cooperation is vital for assuring food safety, and may lead to developing better forms of biocontrol.

miDiagnostics launches its CE-IVD certified ultra-fast COVID-19 PCR test

miDiagnostics welcomes Nicolas De Clercq as its new Chief Financial Officer

Antimicrobial Resistance – the hidden killer we’re ignoring

Antimicrobial Resistance has become an enormous challenge for global health, yet remains largely ignored by companies. As this deadly race worsens, we urgently need to address the huge mismatch between the need and incentive for developing new antimicrobial drugs.