Intressa Vascular secures EUR 18 million in financing to support the development of its multilayer Allay™ Aortic Stent for the treatment of aortic dissection

Intressa Vascular is using its proprietary stent braiding technology to develop an innovative multilayer stent for the treatment of aortic dissection, a life-threatening cardiovascular condition affecting worldwide 300,000 patients annually. The company has secured EUR 18 million in financing with the support of new investors and the Walloon Region. Funds are aimed at clinical studies and product registration purposes.
Dr. Federico Mingozzi is the CSO of Spark Therapeutics, the company behind Luxturna – the world’s first FDA-approved gene therapy for a genetic disease. Though we like to focus on success stories like Luxturna, the reality is that gene therapy is a new modality, and the field is still developing. We spoke to Dr. Mingozzi about some of the technical challenges currently hampering progress in gene therapy, and how people are working together to overcome these hurdles.
Preventing cardiovascular diseases before the first symptoms arise? That’s the ambition of SPINOVIT – a Louvain-La-Neuve company using a new biomarker and innovative technology to achieve its goal. A large clinical trial should be finished in 2023, after which the young company’s product will be launched on the market. In the long term, SPINOVIT’s solution could become part of people’s annual blood check-ups.
Beer, chocolate, and… biotech! When it comes to life sciences, Belgium excels. It consistently ranks as one of the world’s top countries for innovation and R&D. But Belgians are generally a modest bunch: despite being part of a world-class ecosystem, few tend to broadcast that news abroad, or even within our own borders. As a consequence, the Belgian science sector doesn’t receive the recognition it deserves. Which is where BioVox comes in!
The microbiome has been a trending scientific topic in recent years. Researchers have uncovered correlations between the human microbiome and a wide range of diseases and health states, ranging from digestive issues to mental wellbeing. But no matter how fascinating these academic findings may be, translating them into concrete clinical applications remains a challenge. How can we enable more efficient clinical valorization of microbiome insights, and pave the way from pattern to patient?
Dr. Monica Bennett is Head of Gene Therapy Unit at Novartis, the company behind the world’s only gene therapy approved for a neurological indication. Zolgensma treats children with spinal muscular atrophy (SMA), a genetic condition where infants with the most severe type rarely survive past their first few years of life. We spoke to Dr. Bennett about her experience working with SMA kids and their families, and the inspiring potential of gene therapy in other neurological diseases.
VIB’s new incubator program biotope fosters early biotech startups looking to impact people’s lives through agrifood innovation. Based in the heart of a flourishing ecosystem, biotope supports young companies looking to de-risk their technology, build a viable business case, and connect with expert scientists, industry leaders, and investors. The aim is to create mutual benefit for both the ecosystem and the entrepreneurs – providing the region with an influx of talent and innovation, and the startup teams with the support and brains they need to grow and succeed.
Dr. Katherine High is one of gene therapy’s pioneers, who has contributed to a long list of firsts in the field. As President of Spark Therapeutics, Dr. High led the team that developed Luxturna ­– the first FDA-approved gene therapy in the world and the first to be approved in both the US and Europe. Prior to that, her trailblazing clinical work with adeno-associated viral (AAV) vectors helped paved the way for many subsequent gene therapies. Today, Dr. High continues her cutting-edge work as President of Therapeutics at gene therapy company AskBio, a wholly owned subsidiary of Bayer AG. We spoke with Dr. High about the evolution of this fascinating field, which has the potential to provide transformational therapies for so many people with otherwise untreatable genetic diseases.
The vibrant Belgian life sciences sector needs a constant influx of young and ambitious entrepreneurs to sustain its growth. The Solvay Brussels School of Economics and Management has launched a brand-new program to meet this demand, co-developed with key academic and industry stakeholders.
Much has been said about the huge economic potential of algae, but this ‘green gold’ has yet to meet expectations. The European project IDEA – led by Belgian research center VITO – is examining the economic benefits of microalgae and developing strategies to overcome remaining challenges. Interim results show that algae can very well be grown in the climate of Northwestern Europe and can be used to efficiently produce products such as healthy biscuits, animal feed and cosmetic applications.
Data science is booming, including in the healthcare sector. However, in order to extract insights and benefits from our health data, we first have to build a solid system for structural data processing and management. To frame the needs for healthcare data reuse in Belgium, Inovigate has united stakeholders and summarized their recommendations in two white papers.
A veteran of the life sciences industry, Dr. Ajit Shetty continues to have a huge impact on the ecosystem both in Belgium and abroad. Several years after his retirement from top positions in Janssen Pharmaceutica & Johnson and Johnson (as Chair and previously as Managing Director), Shetty is still actively involved in the industry. Awarded the title of Baron by King Albert II of Belgium in 2008 for his services to the sector, and the recipient of Trends ‘Manager of the Year 2004’ and the Life-Time Achievement Award by India (his country of birth), Shetty is a living legend who is still busy shaping the world’s future.
Ghent-based Indigo aims to make a huge difference to the quality of life of people with diabetes. The company is developing a device to render the monitoring of blood sugar levels painless and invisible, a major improvement compared to the tools available today. The innovative technology is based on spectroscopy – using light to measure glucose levels through the skin.