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Belgian initiatives boosting animal-free innovation

Animals have been used throughout history to understand human physiology and to resolve scientific questions related to health and disease. Nowadays, however, both scientists and the public are pushing for better options to animal testing, and so increasing efforts are being put into developing and promoting these alternative methods. Two such initiatives are being spearheaded by the Vrije Universiteit Brussel (VUB): The Innovation Centre for 3R Alternatives (IC-3Rs) and the RE-Place project.

Predictions for Belgian Biotech in 2020

With the Belgian biotech landscape blooming, BioVox reached out to some of the investors in our network to see what their predictions are for the coming year. From trends to companies to keep an eye on, here’s their take on 2020!

Why Are Start-Ups Such Hotbeds For Innovation?

A large proportion of new treatments and life sciences breakthroughs can often be traced back to humble beginnings in a start-up venture. Why is it that these smaller companies seem so adept at developing innovative products? What have they got that larger companies are lacking? V-Bio Ventures takes a look at some of the factors making start-ups hotbeds for innovation.

How business models shaped our current drug development trends

With the soaring cost of drugs for rare indications, many biotech and pharmaceutical companies are focusing R&D efforts on orphan diseases. Will the pendulum swing back towards more common maladies? When will the price of drugs start to fall? In this month’s VC views, V-Bio Ventures examines the current business model for rare diseases.

Magic mushrooms in modern medicine

More than 75 years after the initial discovery of lysergic acid diethylamide (LSD), psilocybin and other natural psychoactive drugs, and their initial exploitation by the western pharma industry, these substances have seen a recent revival in clinical research. Although banned in the notorious “War on Drugs” initiated by US President Nixon, the potential medicinal applications of these substances are finally being explored again, particularly for treating depressive disorders and other mental diseases. This article aims to shed light on a topic we highlighted before in this series - anti-science in biotech - to illustrate the consequences of research being abandoned, as well as the opportunities and additional challenges to making these substances finally available for patients in need.

The 2019 Nobel Prize in Medicine: How do cells adapt to changing oxygen levels?

The 2019 Nobel Prize in Physiology or Medicine was awarded to William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza. Their discoveries have paved the way for promising new strategies to fight anemia, cancer and many other diseases. We’re breaking down the research that led to the prize and why this work was so vital for modern medicine.

Mining the microbiome for sustainable agriculture solutions

In this month’s article we take a look at Aphea.Bio, a V-Bio Ventures portfolio company. This startup is developing microbiome products for improved crop growth and pest protection, using state-of-the art technology.

Closing the gender gap in biotech funding: a follow-up study

In this follow-up to a previous VC Views article, V-Bio Ventures takes a look at several questions that were generated by readers. The VC firm carried out a study of the gender composition of investment teams and the impact of these ratios on investment decisions, reflecting on some strategies that might help women with executive ambitions reach their goals.

Three business strategy tips to help your company grow

Fresh insights into the future of cell therapy

The first edition of Science for health was held in the heart of Brussels on 11th September 2019 with a focus on cell therapy. The event attracted over 300 researchers, clinicians and industry professionals active in the the local or international cell therapy ecosystem. Top-speakers provided interesting insights into the current state of cell therapy in Belgium, as well as requirements for further progress. Collaboration, especially outside of the traditional partnerships, is key.

Galapagos-Gilead billion-dollar deal: beyond the numbers

Last month, Galapagos sealed a 5-billion-dollar deal with Gilead. Now that the dust has started to settle, we’re taking a closer look at the agreement. Why is this deal so unique in the biotech world? What will the ripple effects be in the European ecosystem? BioVox spoke with Lenny Van Steenhuyse, Healthcare Equity Analyst at KBC Securities, for a deeper insight.

Why events are important for creating connections in the life sciences

Collaboration is vital for science. Without cross-pollination of ideas and talent, progress would be excruciatingly slow in both industry and academia. Networking opportunities, like the annual Knowledge for Growth event and Science for health, stimulate research collaboration by connecting people. So, what’s the role of a cluster organization in all this? BioVox spoke with flanders.bio representatives Pascale Engelen and Katrien Lorré to find out.

Meet the men who unraveled the mystery of protein folding

Franz-Ulrich Hartl and Arthur Horwich have been named the winners of the 2019 Dr. Paul Janssen Award for Biomedical Research. The award will be granted for their revolutionary insights into chaperone-mediated protein folding, a key process for biological function. The winners will share their insights during the annual award ceremony, which will be celebrated both at the Janssen Beerse Campus in Belgium on September 27 and at the New York Academy of Sciences in the US on October 3, providing attendees with a unique opportunity to meet two of the world’s leading scientists.

The million-dollar question: How much do you charge for a lifesaving drug?

The newest generation of ground-breaking gene therapy drugs, Zolgensma and Zynteglo, come with eye-catching price tags of more than a million dollars per treatment. Is the pharma industry recklessly overstepping a line here, or do they fall within current standards of value-based drug pricing? With more of these drugs soon to be rolling out of pharma pipelines, the stakes are rising high for patients, industry, governments, health insurance companies, as well as investors. It all warrants a deeper dive into the case.

How do we reduce the high cost of clinical trials?

Drug development is an exorbitantly expensive endeavor. A large expense factor for developing a new therapy is the high cost of conducting clinical trials. Why are clinical trials so insanely expensive to run? And what can be done to increase the affordability of these trials?