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Biomedical/pharma

Biomedical/pharma, Healthcare technology, Personal/public health, Public health

Luxembourg’s Vision for a Digital HealthTech Future

Luxembourg may be one of the smallest nations in the world, at just over 2,500 square kilometers and around 670,000 inhabitants, but it packs a punch in the global life sciences ecosystem. With world-class research institutes, startup accelerators, and the country’s growing digital prowess, Luxembourg is attracting global talent and putting digital healthtech solutions front and center. So, how did the Grand Duchy establish and grow its thriving research and startup landscape, and what is the vision for the future?

The gut and the bad: How technology can help us uncover the links between our food, gut microbiome, and human health

In our overfed yet undernourished modern society, we must understand how the things we eat contribute to our gut microbiome and overall health. Analyzing how the friendly and not-so-friendly communities of microbes in our gut respond to our daily intake of food, additives, supplements, and pharmaceuticals will help companies formulate more nutritious products while providing us with crucial insights to help us all be healthier for longer.

Human brain organoids for Parkinson’s disease research – A helping hand from Luxembourg

Could we ever recreate the complexity of the human brain in the lab? Over ten years ago, researchers aimed to do just that by developing a three-dimensional cell culture method to grow the first ever miniaturized versions of the human brain, so-called ‘brain organoids.’ Innovation in this field continues at a rapid pace, with researchers in Luxembourg and around the world refining methods to grow organoids that resemble specific brain regions. These advances can help us understand the effects of Parkinson’s disease on cells while driving the discovery of novel therapeutics beneficial to those in need.

On our way to saving minds: the current status of Alzheimer’s disease drug discovery

An ageing population comes with multiple challenges. Diseases affecting older populations are becoming more prevalent shifting the focus of our healthcare systems. One of the most debilitating is Alzheimer’s disease. Although there is currently no cure, groundbreaking research is expanding our knowledge, giving hope to patients.

Anacura acquires OHMX.bio, adding multi-omics for drug discovery and diagnostics to its services

Anacura, a Ghent-based company offering medical and pharmaceutical analytical services, announces the acquisition of OHMX.bio, a Ghent University spin-off specialized in advanced -omics technology. The acquisition expands the existing anacura group activities at AnaBioTec and Labo Nuytinck towards drug discovery and diagnostics research.

Axithra Strengthens its Board of Directors

The appointments of Dr. Alain Pluquet as Chairman of the Board and Mr. Michael Tillmann as Independent Director brings extensive industrial expertise to help develop Axithra’s long-term strategy

A Guide to the OMOP Common Data Model

The Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM) is a standardized framework designed by the Observational Health Data Sciences and Informatics (OHDSI) community. This open-science community aims to improve the quality of healthcare by providing guidelines for a more harmonized approach to data science.

Gender personalized medicine: the future of fatty liver disease treatment

In a world where our health is paramount, fatty liver disease, known as metabolic dysfunction-associated steatotic liver disease (MASLD), is climbing the ranks of health concerns we can't afford to ignore. Imagine your liver, which controls over 500 vital functions, including the body's detox powerhouse, getting clogged with fat. Alarmingly, about 30% of people globally are wrestling against this silent epidemic. It's a complex disease with various risk factors, especially related to gender and sex hormonal differences, making a one-size-fits-all treatment difficult.

V-Bio Ventures leads €20 million Series A financing of Precision oncology company Flindr Therapeutics to advance first-in-class small molecule inhibitors

Using patient data to enable personalized healthcare, ATHENA shows us how!

Personalized healthcare is characterized by tailoring treatments to each individual patient’s needs. Despite evident benefits, implementing such a system is not straightforward. The ATHENA project consortium has successfully devised a set of building blocks to address the challenges associated. Both technological and governance tools were developed that can now be used on a larger scale to catalyze the transition towards personalized medicine and care.

From successful conception to a healthy family – Belgian research raises the bar for IVF

Belgium is one of the top countries in the world for in vitro fertilization (IVF). Despite the high cumulative success rates of these interventions, disproportionally little attention has been given to the health of both mother and child during and after pregnancy. With the HEART (High risk for pre-Eclampsia after Assisted Reproductive Technology) project, Belgian researchers strive to understand why some women have an increased risk for pre-eclampsia after IVF and whether biomarkers can be identified to estimate these risks early in pregnancy or even before conception. They aim to raise the standard from successful conception to improved child and maternal health.

This vagina-on-chip model holds the potential to advance yeast infection research

While a vast majority of women experience vaginal yeast infections, research has fallen short in providing an effective treatment approach. However, hope has emerged recently with the development of new model systems that allow exploration of the complex vaginal environment. Organ-on-chip models enable researchers to examine the interactions between human cells and microbes in a more accurate manner, offering the potential for the development of new therapies.

Fund+ portfolio company Cardior Pharmaceuticals to be acquired by Novo Nordisk in potential 1-billion-euro deal

Novo Nordisk will acquire Cardior Pharmaceuticals for up to 1.025 billion euros, including upfront and additional payments if certain development and commercial milestones are achieved. Cardior is a leader in RNA-based therapies that have the potential to prevent, repair and reverse diseases of the heart. The company’s approach targets distinctive non-coding RNAs to address the root causes of cardiac dysfunctions and achieve lasting patient impact.

Fund+ Portfolio Company Tubulis Closes Upsized EUR 128 Million Series B2 to Accelerate Clinical Development of Solid Tumor-Focused ADC Pipeline

Bridging the immunity gap: improving animal welfare without antibiotics

Antibiotic resistance is a major concern for humans and animals. Increasing pressure to move away from antibiotics has created space for new solutions for disease management. Animab’s oral monoclonal antibody platform is a promising alternative, effectively guarding against infection during a vulnerable period in an animal’s development.