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Public health

Personal/public health, Public health

Antibiotic guidelines for food might underestimate the risk for bacterial resistance

Even ‘safe’ levels of antibiotics in food might fuel the next generation of superbugs. Even tiny traces of antibiotics in the meat and fish we eat could contribute to antibiotic resistance. According to research by the Institute of Tropical Medicine (ITM) in Antwerp, as little as one tenth of the amount of antibiotics currently regarded as ‘safe’ by regulators is enough to trigger resistance in bacteria. Now, the scientists are expanding their research, initially performed on wax moth larvae, to mice and humans.

Luxembourg’s Vision for a Digital HealthTech Future

Luxembourg may be one of the smallest nations in the world, at just over 2,500 square kilometers and around 670,000 inhabitants, but it packs a punch in the global life sciences ecosystem. With world-class research institutes, startup accelerators, and the country’s growing digital prowess, Luxembourg is attracting global talent and putting digital healthtech solutions front and center. So, how did the Grand Duchy establish and grow its thriving research and startup landscape, and what is the vision for the future?

A data-driven solution to get children on the move

Children increasingly seek the comfort and entertainment of television, tablets and smartphones rather than playing outside. This reduction in physical activity has accelerated over the last few decades and has detrimental effects for children later in life. They are the future, so studying their development and lifestyle gives us a forecast of where we are heading. Are we moving towards a sedentary population? And if so, how can we alter our course?

Athlete versus pain, an inevitable battle?

Training session after training session, top athletes must push themselves to the limits to test their bodies. Although pain is a clear emergency signal, athletes in pain may push themselves even further. This makes them vulnerable to injuries and severe pain conditions including acute and chronic lower back pain. Although there are several treatment options to alleviate the symptoms, the treatment of acute and chronic pain is not straightforward. A multidisciplinary approach is required, and more treatment options are needed that focus on treating the underlying cause.

Will the looming pharma patent cliff start driving a super cycle of biotech deals?

After several years of dismal market activity, 2024 is already looking up for deals in the pharmaceutical industry, with a recent flurry of billion-dollar mergers and acquisitions. Is this trend being driven by the impending loss of revenue caused by soon-to-expire blockbuster drug patents? And what does it mean for earlier-stage biotech startups?

From successful conception to a healthy family – Belgian research raises the bar for IVF

Belgium is one of the top countries in the world for in vitro fertilization (IVF). Despite the high cumulative success rates of these interventions, disproportionally little attention has been given to the health of both mother and child during and after pregnancy. With the HEART (High risk for pre-Eclampsia after Assisted Reproductive Technology) project, Belgian researchers strive to understand why some women have an increased risk for pre-eclampsia after IVF and whether biomarkers can be identified to estimate these risks early in pregnancy or even before conception. They aim to raise the standard from successful conception to improved child and maternal health.

Retaining female talents

While the life sciences environment is adjusting to be able to foster female talents in the workplace, there is still a long way to go to achieve truly egalitarian work conditions. From the ‘motherhood penalty’ to unconscious bias, women can still be made to feel unwelcome in their daily work life. This is what motivated Veroniek Vermeulen to launch Silatha, a company with the goal of creating an environment where everyone can thrive.

This vagina-on-chip model holds the potential to advance yeast infection research

While a vast majority of women experience vaginal yeast infections, research has fallen short in providing an effective treatment approach. However, hope has emerged recently with the development of new model systems that allow exploration of the complex vaginal environment. Organ-on-chip models enable researchers to examine the interactions between human cells and microbes in a more accurate manner, offering the potential for the development of new therapies.

Belgian breakthrough in endometriosis research captures investors’ attention

Even though endometriosis impacts millions of women globally, the condition remains poorly understood and researched, leading to delayed diagnosis and lack of effective treatment. Encouragingly, there are promising recent developments in the field coming from Belgium. Professor Hugo Vankelecom’s research group at KU Leuven uses advanced cellular models, known as organoids, to delve into the disease and expedite the drug discovery process. The Danish BioInnovation Institute now offers the team an incubation program to pave the way towards industrial success.

The rise of women’s health

It’s been a Barbie world this summer with crowds of pink-clad moviegoers flooding the cinemas. Simultaneously, we’ve been witnessing a rush of ‘pink’ fundraising for women’s health start-ups. From pre-clinical to clinical: more companies are entering the field and developing solutions for women’s unique needs. But is their focus broad and innovative enough? And are pharma companies paying attention?

Using real-world data for post-market surveillance of drug safety

After a therapeutic drug hits the market, it is crucial to continuously gather, analyze, and report data regarding its safety and potential side effects, a practice known as pharmacovigilance. Unlike clinical trials, this involves real-world data (RWD), presenting unique challenges in terms of both quality and quantity. The Belgian BELpREG project seeks to employ RWD for monitoring drug utilization during pregnancy and investigating potential safety implications for both maternal and child health. This initiative holds great promise, although it faces substantial hurdles on its path to success.

How to integrate patient perspectives in innovation

After recovering from metastatic colon cancer, Stefan Gijssels became a patient advocate dedicated to improving the healthcare system that saved his life. As Chair of the Belgian Patient Expert Center (PEC), he has helped to establish a training program turning patients into patient experts who can provide stakeholders like hospitals and companies with valuable insights during the innovation process.

Femtech: Breaking barriers in women’s health through innovation and investment

Femtech is a growing field that has rapidly expanded from niche market to global ecosystem. From period-tracking apps and smart pelvic floor trainers to wearable breast pumps – both start-ups and well-established multinationals are prioritizing tech innovation in women’s health. But are investors keeping up with this trend, or is the strong gender skew in venture capital hampering the femtech field?

The chaos of choice: how do people pick their food products?

Every family needs groceries, and most people regularly venture to the supermarket to gather supplies. If researchers can help shoppers make healthier choices, we can improve the obesity problem in a simple yet effective way. But until recently, nobody really understood what motivated people to choose certain products – we knew what they bought, but not why. We’ve therefore investigated shoppers’ choice strategies, hoping to use this information to help people choose healthier.

From multiple pills per day to one treatment per month: progress in HIV medication made possible by pharma collaborations

Unprecedented collaborations between different pharmaceutical companies have resulted in extraordinary progress for HIV patients over the past four decades. From the first ever treatments, to single pills and now even long-acting injections, treatment options have come a long way. In this interview, Dr. Theresa Pattery (Head of Disease Management Programs at Janssen Pharmaceutica) tells us of this long journey and talks about the role of drones and phones in the world-wide fight against HIV.